Prothrombotic effects of tumor necrosis factor alpha in vivo are amplified by the absence of TNF-alpha receptor subtype 1 and require TNF-alpha receptor subtype 2

INTRODUCTION: Elevated serum levels of the proinflammatory cytokine tumor necrosis factor alpha (TNFα) correlate with an increased risk for atherothrombotic events and TNFα is known to induce prothrombotic molecules in endothelial cells. Based on the preexisting evidence for the impact of TNFα in th...

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Detalles Bibliográficos
Autores principales: Pircher, Joachim, Merkle, Monika, Wörnle, Markus, Ribeiro, Andrea, Czermak, Thomas, Stampnik, Yvonn, Mannell, Hanna, Niemeyer, Markus, Vielhauer, Volker, Krötz, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580536/
https://www.ncbi.nlm.nih.gov/pubmed/23079185
http://dx.doi.org/10.1186/ar4064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580536/
https://www.ncbi.nlm.nih.gov/pubmed/23079185
http://dx.doi.org/10.1186/ar4064

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