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Differential effects of Th1 versus Th2 cytokines in combination with hypoxia on HIFs and angiogenesis in RA
INTRODUCTION: Hypoxia and T-helper cell 1 (Th1) cytokine-driven inflammation are key features of rheumatoid arthritis (RA) and contribute to disease pathogenesis by promoting angiogenesis. The objective of our study was to characterise the angiogenic gene signature of RA fibroblast-like synoviocytes...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580575/ https://www.ncbi.nlm.nih.gov/pubmed/22866899 http://dx.doi.org/10.1186/ar3934 |