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Cartilage oligomeric matrix protein specific antibodies are pathogenic

INTRODUCTION: Cartilage oligomeric matrix protein (COMP) is a major non-collagenous component of cartilage. Earlier, we developed a new mouse model for rheumatoid arthritis using COMP. This study was undertaken to investigate the epitope specificity and immunopathogenicity of COMP-specific monoclona...

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Detalles Bibliográficos
Autores principales: Geng, Hui, Nandakumar, Kutty Selva, Pramhed, Anna, Aspberg, Anders, Mattsson, Ragnar, Holmdahl, Rikard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580587/
https://www.ncbi.nlm.nih.gov/pubmed/22906101
http://dx.doi.org/10.1186/ar4022