Depletion of neutrophil extracellular traps in vivo results in hypersusceptibility to polymicrobial sepsis in mice

INTRODUCTION: Although the formation of neutrophil (PMN) extracellular traps (NETs) has been detected during infection and sepsis, their role in vivo is still unclear. This study was performed in order to evaluate the influence of NETs depletion by administration of recombinant human (rh)DNase on ba...

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Detalles Bibliográficos
Autores principales: Meng, Wei, Paunel-Görgülü, Adnana, Flohé, Sascha, Hoffmann, Almuth, Witte, Ingo, MacKenzie, Colin, Baldus, Stephan E, Windolf, Joachim, Lögters, Tim T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580722/
https://www.ncbi.nlm.nih.gov/pubmed/22835277
http://dx.doi.org/10.1186/cc11442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580722/
https://www.ncbi.nlm.nih.gov/pubmed/22835277
http://dx.doi.org/10.1186/cc11442

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