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Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis

INTRODUCTION: Hyperglycemia and insulin resistance have been associated with a worse outcome in sepsis. Although tight glycemic control through insulin therapy has been shown to reduce morbidity and mortality rates, the effect of intensive insulin therapy in patients with severe sepsis is controvers...

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Detalles Bibliográficos
Autores principales: Calisto, Kelly L, Camacho, Angélica C, Mittestainer, Francine C, Carvalho, Bruno M, Guadagnini, Dioze, Carvalheira, José B, Saad, Mario J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580748/
https://www.ncbi.nlm.nih.gov/pubmed/22897821
http://dx.doi.org/10.1186/cc11478