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A New Dual-Promoter System for Cardiomyocyte-Specific Conditional Induction of Apoptosis

Apoptosis is a key determinant of major pathological processes, including chronic cardiac failure. We developed and tested in vitro a novel system to induce cardiomyocyte-specific apoptosis by virus-mediated delivery of a conditional transgene. The entire system was packaged in a lentiviral vector....

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Detalles Bibliográficos
Autores principales: Agostini, Silvia, Lionetti, Vincenzo, Matteucci, Marco, Chiuppesi, Flavia, Giacca, Mauro, Pistello, Mauro, Recchia, Fabio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581143/
https://www.ncbi.nlm.nih.gov/pubmed/23573514
http://dx.doi.org/10.1155/2013/845816