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A New Dual-Promoter System for Cardiomyocyte-Specific Conditional Induction of Apoptosis
Apoptosis is a key determinant of major pathological processes, including chronic cardiac failure. We developed and tested in vitro a novel system to induce cardiomyocyte-specific apoptosis by virus-mediated delivery of a conditional transgene. The entire system was packaged in a lentiviral vector....
Autores principales: | Agostini, Silvia, Lionetti, Vincenzo, Matteucci, Marco, Chiuppesi, Flavia, Giacca, Mauro, Pistello, Mauro, Recchia, Fabio A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581143/ https://www.ncbi.nlm.nih.gov/pubmed/23573514 http://dx.doi.org/10.1155/2013/845816 |
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