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Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

Conditional gene targeting has been extensively used for in vivo analysis of gene function in adipocyte cell biology but often with debate over the tissue specificity and the efficacy of inactivation. To directly compare the specificity and efficacy of different Cre lines in mediating adipocyte spec...

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Detalles Bibliográficos
Autores principales: Lee, Kevin Y., Russell, Steven J., Ussar, Siegfried, Boucher, Jeremie, Vernochet, Cecile, Mori, Marcelo A., Smyth, Graham, Rourk, Michael, Cederquist, Carly, Rosen, Evan D., Kahn, Barbara B., Kahn, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581196/
https://www.ncbi.nlm.nih.gov/pubmed/23321074
http://dx.doi.org/10.2337/db12-1089