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Inhibition of Carnitine Palmitoyltransferase-1 Activity Alleviates Insulin Resistance in Diet-Induced Obese Mice

Impaired skeletal muscle fatty acid oxidation has been suggested to contribute to insulin resistance and glucose intolerance. However, increasing muscle fatty acid oxidation may cause a reciprocal decrease in glucose oxidation, which might impair insulin sensitivity and glucose tolerance. We therefo...

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Detalles Bibliográficos
Autores principales: Keung, Wendy, Ussher, John R., Jaswal, Jagdip S., Raubenheimer, Monique, Lam, Victoria H.M., Wagg, Cory S., Lopaschuk, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581198/
https://www.ncbi.nlm.nih.gov/pubmed/23139350
http://dx.doi.org/10.2337/db12-0259