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Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders such as obesity and diabetes that are often linked with defects in oxidative metabolism. Here, we evaluated the potential of class-specific s...

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Detalles Bibliográficos
Autores principales: Galmozzi, Andrea, Mitro, Nico, Ferrari, Alessandra, Gers, Elise, Gilardi, Federica, Godio, Cristina, Cermenati, Gaia, Gualerzi, Alice, Donetti, Elena, Rotili, Dante, Valente, Sergio, Guerrini, Uliano, Caruso, Donatella, Mai, Antonello, Saez, Enrique, De Fabiani, Emma, Crestani, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581211/
https://www.ncbi.nlm.nih.gov/pubmed/23069623
http://dx.doi.org/10.2337/db12-0548