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MicroRNA-7 Regulates the mTOR Pathway and Proliferation in Adult Pancreatic β-Cells

Elucidating the mechanism underlying the poor proliferative capacity of adult pancreatic β-cells is critical to regenerative therapeutic approaches for diabetes. Here, we show that the microRNA (miR)-7/7ab family member miR-7a is enriched in mouse adult pancreatic islets compared with miR-7b. Remark...

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Detalles Bibliográficos
Autores principales: Wang, You, Liu, Jiangying, Liu, Chengyang, Naji, Ali, Stoffers, Doris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581216/
https://www.ncbi.nlm.nih.gov/pubmed/23223022
http://dx.doi.org/10.2337/db12-0451