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Inverse Regulation of Inflammation and Mitochondrial Function in Adipose Tissue Defines Extreme Insulin Sensitivity in Morbidly Obese Patients

Obesity is associated with insulin resistance, a major risk factor for type 2 diabetes and cardiovascular disease. However, not all obese individuals are insulin resistant, which confounds our understanding of the mechanistic link between these conditions. We conducted transcriptome analyses on 835...

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Detalles Bibliográficos
Autores principales: Qatanani, Mohammed, Tan, Yejun, Dobrin, Radu, Greenawalt, Danielle M., Hu, Guanghui, Zhao, Wenqing, Olefsky, Jerrold M., Sears, Dorothy D., Kaplan, Lee M., Kemp, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581230/
https://www.ncbi.nlm.nih.gov/pubmed/23223024
http://dx.doi.org/10.2337/db12-0399