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Inverse Regulation of Inflammation and Mitochondrial Function in Adipose Tissue Defines Extreme Insulin Sensitivity in Morbidly Obese Patients
Obesity is associated with insulin resistance, a major risk factor for type 2 diabetes and cardiovascular disease. However, not all obese individuals are insulin resistant, which confounds our understanding of the mechanistic link between these conditions. We conducted transcriptome analyses on 835...
Autores principales: | Qatanani, Mohammed, Tan, Yejun, Dobrin, Radu, Greenawalt, Danielle M., Hu, Guanghui, Zhao, Wenqing, Olefsky, Jerrold M., Sears, Dorothy D., Kaplan, Lee M., Kemp, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581230/ https://www.ncbi.nlm.nih.gov/pubmed/23223024 http://dx.doi.org/10.2337/db12-0399 |
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