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Signal Transducer and Activator of Transcription Factor 6 Signaling Contributes to Control Host Lung Pathology but Favors Susceptibility against Toxocara canis Infection

Using STAT6(−/−) BALB/c mice, we have analyzed the role of STAT6-induced Th2 response in determining the outcome of experimental toxocariasis caused by embryonated eggs of the helminth parasite Toxocara canis. Following T. canis infection wild-type BALB/c mice developed a strong Th2-like response, p...

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Detalles Bibliográficos
Autores principales: Faz-López, Berenice, Ledesma-Soto, Yadira, Romero-Sánchez, Yolanda, Calleja, Elsa, Martínez-Labat, Pablo, Terrazas, Luis I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581294/
https://www.ncbi.nlm.nih.gov/pubmed/23509764
http://dx.doi.org/10.1155/2013/696343