Cargando…
Autophagy and Cellular Senescence Mediated by Sox2 Suppress Malignancy of Cancer Cells
Autophagy is a critical cellular process required for maintaining cellular homeostasis in health and disease states, but the molecular mechanisms and impact of autophagy on cancer is not fully understood. Here, we found that Sox2, a key transcription factor in the regulation of the “stemness” of emb...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581442/ https://www.ncbi.nlm.nih.gov/pubmed/23451179 http://dx.doi.org/10.1371/journal.pone.0057172 |