Cargando…

Autophagy and Cellular Senescence Mediated by Sox2 Suppress Malignancy of Cancer Cells

Autophagy is a critical cellular process required for maintaining cellular homeostasis in health and disease states, but the molecular mechanisms and impact of autophagy on cancer is not fully understood. Here, we found that Sox2, a key transcription factor in the regulation of the “stemness” of emb...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Yong-Yeon, Kim, Dong Joon, Lee, Hye Suk, Jeong, Chul-Ho, Cho, Eun-Jin, Kim, Myong-Ok, Byun, Sanguine, Lee, Kun-Yeong, Yao, Ke, Carper, Andria, Langfald, Alyssa, Bode, Ann M., Dong, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581442/
https://www.ncbi.nlm.nih.gov/pubmed/23451179
http://dx.doi.org/10.1371/journal.pone.0057172