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VPO1 Mediates ApoE Oxidation and Impairs the Clearance of Plasma Lipids
OBJECTIVE: ApoE is an abundant component of chylomicron, VLDL, IDL, and HDL. It binds to multiple types of lipids and is implicated in cholesterol and triglyceride homeostasis. Oxidation of ApoE plays a crucial role in the genesis of atherosclerosis. It is proposed that heme-containing peroxidases (...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581477/ https://www.ncbi.nlm.nih.gov/pubmed/23451244 http://dx.doi.org/10.1371/journal.pone.0057571 |