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VPO1 Mediates ApoE Oxidation and Impairs the Clearance of Plasma Lipids

OBJECTIVE: ApoE is an abundant component of chylomicron, VLDL, IDL, and HDL. It binds to multiple types of lipids and is implicated in cholesterol and triglyceride homeostasis. Oxidation of ApoE plays a crucial role in the genesis of atherosclerosis. It is proposed that heme-containing peroxidases (...

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Detalles Bibliográficos
Autores principales:	Yang, Youfeng, Cao, Zehong, Tian, Ling, Garvey, W. Timothy, Cheng, Guangjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581477/ https://www.ncbi.nlm.nih.gov/pubmed/23451244 http://dx.doi.org/10.1371/journal.pone.0057571

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