Genome Wide Mapping Reveals PDE4B as an IL-2 Induced STAT5 Target Gene in Activated Human PBMCs and Lymphoid Cancer Cells

IL-2 is the primary growth factor for promoting survival and proliferation of activated T cells that occurs following engagement of the Janus Kinase (JAK)1–3/and Signal Transducer and Activator of Transcription (STAT) 5 signaling pathway. STAT5 has two isoforms: STAT5A and STAT5B (commonly referred...

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Detalles Bibliográficos
Autores principales: Nagy, Zsuzsanna S., Ross, Jeremy A., Rodriguez, Georgialina, Balint, Balint L., Szeles, Lajos, Nagy, Laszlo, Kirken, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581501/
https://www.ncbi.nlm.nih.gov/pubmed/23451206
http://dx.doi.org/10.1371/journal.pone.0057326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581501/
https://www.ncbi.nlm.nih.gov/pubmed/23451206
http://dx.doi.org/10.1371/journal.pone.0057326

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