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Biochemical and Mutational Analysis of a Novel Nicotinamidase from Oceanobacillus iheyensis HTE831

Nicotinamidases catalyze the hydrolysis of nicotinamide to nicotinic acid and ammonia, an important reaction in the NAD(+) salvage pathway. This paper reports a new nicotinamidase from the deep-sea extremely halotolerant and alkaliphilic Oceanobacillus iheyensis HTE831 (OiNIC). The enzyme was active...

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Detalles Bibliográficos
Autores principales: Sánchez-Carrón, Guiomar, García-García, María Inmaculada, Zapata-Pérez, Rubén, Takami, Hideto, García-Carmona, Francisco, Sánchez-Ferrer, Álvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581539/
https://www.ncbi.nlm.nih.gov/pubmed/23451075
http://dx.doi.org/10.1371/journal.pone.0056727