Small Intestine Inflammation in Roquin-Mutant and Roquin-Deficient Mice

Roquin, an E3 ubiquitin ligase that localizes to cytosolic RNA granules, is involved in regulating mRNA stability and translation. Mice that have a M199R mutation in the Roquin protein (referred to as sanroque or Roquin(san/san) mice) develop autoimmune pathologies, although the extent to which thes...

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Detalles Bibliográficos
Autores principales: Schaefer, Jeremy S., Montufar-Solis, Dina, Nakra, Niyati, Vigneswaran, Nadarajah, Klein, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581552/
https://www.ncbi.nlm.nih.gov/pubmed/23451046
http://dx.doi.org/10.1371/journal.pone.0056436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581552/
https://www.ncbi.nlm.nih.gov/pubmed/23451046
http://dx.doi.org/10.1371/journal.pone.0056436

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