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Small Intestine Inflammation in Roquin-Mutant and Roquin-Deficient Mice
Roquin, an E3 ubiquitin ligase that localizes to cytosolic RNA granules, is involved in regulating mRNA stability and translation. Mice that have a M199R mutation in the Roquin protein (referred to as sanroque or Roquin(san/san) mice) develop autoimmune pathologies, although the extent to which thes...
Autores principales: | Schaefer, Jeremy S., Montufar-Solis, Dina, Nakra, Niyati, Vigneswaran, Nadarajah, Klein, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581552/ https://www.ncbi.nlm.nih.gov/pubmed/23451046 http://dx.doi.org/10.1371/journal.pone.0056436 |
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