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New Approaches of PARP-1 Inhibitors in Human Lung Cancer Cells and Cancer Stem-Like Cells by Some Selected Anthraquinone-Derived Small Molecules

Poly (ADP-ribose) polymerase-1 (PARP-1) and telomerase, as well as DNA damage response pathways are targets for anticancer drug development, and specific inhibitors are currently under clinical investigation. The purpose of this work is to evaluate anticancer activities of anthraquinone-derived tric...

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Detalles Bibliográficos
Autores principales: Lee, Yu-Ru, Yu, Dah-Shyong, Liang, Ya-Chun, Huang, Kuo-Feng, Chou, Shih-Jie, Chen, Tsung-Chih, Lee, Chia-Chung, Chen, Chun-Liang, Chiou, Shih-Hwa, Huang, Hsu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581553/
https://www.ncbi.nlm.nih.gov/pubmed/23451039
http://dx.doi.org/10.1371/journal.pone.0056284