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Suppression of the Macrophage Proteasome by Ethanol Impairs MHC Class I Antigen Processing and Presentation

Alcohol binge-drinking (acute ethanol consumption) is immunosuppressive and alters both the innate and adaptive arms of the immune system. Antigen presentation by macrophages (and other antigen presenting cells) represents an important function of the innate immune system that, in part, determines t...

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Detalles Bibliográficos
Autores principales: D’Souza, Alain J., Desai, Shyamal D., Rudner, Xiaowen L., Kelly, Michelle N., Ruan, SanBao, Shellito, Judd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581560/
https://www.ncbi.nlm.nih.gov/pubmed/23451104
http://dx.doi.org/10.1371/journal.pone.0056890