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Suppression of the Macrophage Proteasome by Ethanol Impairs MHC Class I Antigen Processing and Presentation
Alcohol binge-drinking (acute ethanol consumption) is immunosuppressive and alters both the innate and adaptive arms of the immune system. Antigen presentation by macrophages (and other antigen presenting cells) represents an important function of the innate immune system that, in part, determines t...
Autores principales: | D’Souza, Alain J., Desai, Shyamal D., Rudner, Xiaowen L., Kelly, Michelle N., Ruan, SanBao, Shellito, Judd E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581560/ https://www.ncbi.nlm.nih.gov/pubmed/23451104 http://dx.doi.org/10.1371/journal.pone.0056890 |
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