MCM-BP Is Required for Repression of Life-Cycle Specific Genes Transcribed by RNA Polymerase I in the Mammalian Infectious Form of Trypanosoma brucei

Trypanosoma brucei variant surface glycoprotein (VSG) expression is a classic example of allelic exclusion. While the genome of T. brucei contains >2,000 VSG genes and VSG pseudogenes, only one allele is expressed at the surface of each infectious trypanosome and the others are repressed. Along w...

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Detalles Bibliográficos
Autores principales: Kim, Hee-Sook, Park, Sung Hee, Günzl, Arthur, Cross, George A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581582/
https://www.ncbi.nlm.nih.gov/pubmed/23451133
http://dx.doi.org/10.1371/journal.pone.0057001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581582/
https://www.ncbi.nlm.nih.gov/pubmed/23451133
http://dx.doi.org/10.1371/journal.pone.0057001

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