Protective effects of an anti-melanocortin-4 receptor scFv derivative in lipopolysaccharide-induced cachexia in rats

BACKGROUND: Cachexia is a complex syndrome defined by weight loss due to an ongoing loss of skeletal muscle mass with or without loss of body fat. It is often associated with anorexia. Numerous results from experimental studies suggest that blockade of the melanocortin-4 receptor (MC4R) could be an...

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Detalles Bibliográficos
Autores principales: Peter, Jean-Christophe, Rossez, Hélène, Weckering, Marjorie, Zipfel, Géraldine, Lecourt, Anne-Catherine, Owen, Joshua B., Banks, William A., Hofbauer, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581610/
https://www.ncbi.nlm.nih.gov/pubmed/22911214
http://dx.doi.org/10.1007/s13539-012-0084-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581610/
https://www.ncbi.nlm.nih.gov/pubmed/22911214
http://dx.doi.org/10.1007/s13539-012-0084-4

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