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Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model

BACKGROUND: In chronic heart failure (CHF), cachexia is a hallmark of the terminal stage of this disease and is associated with a severely reduced quality of life and poor prognosis. Therapeutic options are currently not available. Ghrelin and its analogues BIM-28125 and BIM-28131 (now known as RM-1...

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Detalles Bibliográficos
Autores principales: Lenk, Karsten, Palus, Sandra, Schur, Robert, Datta, Rakesh, Dong, Jesse, Culler, Michael D., Anker, Stefan, Springer, Jochen, Schuler, Gerhard, Adams, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581616/
https://www.ncbi.nlm.nih.gov/pubmed/22987245
http://dx.doi.org/10.1007/s13539-012-0085-3