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Flavonoid regulation of EAG1 channels

The voltage-gated, K(+)-selective ether á go-go 1 (EAG1) channel is expressed throughout the brain where it is thought to regulate neuronal excitability. Besides its normal physiological role in the brain, EAG1 is abnormally expressed in several cancer cell types and promotes tumor progression. Like...

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Detalles Bibliográficos
Autores principales: Carlson, Anne E., Brelidze, Tinatin I., Zagotta, William N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581696/
https://www.ncbi.nlm.nih.gov/pubmed/23440277
http://dx.doi.org/10.1085/jgp.201210900