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Regulation of AQP0 water permeability is enhanced by cooperativity

Aquaporin 0 (AQP0), essential for lens clarity, is a tetrameric protein composed of four identical monomers, each of which has its own water pore. The water permeability of AQP0 expressed in Xenopus laevis oocytes can be approximately doubled by changes in calcium concentration or pH. Although each...

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Detalles Bibliográficos
Autores principales: Németh-Cahalan, Karin L., Clemens, Daniel M., Hall, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581697/
https://www.ncbi.nlm.nih.gov/pubmed/23440275
http://dx.doi.org/10.1085/jgp.201210884