Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals

N-Glycosylation is a common post-translational modification of monoclonal antibodies with a potential effect on the efficacy and safety of the drugs; detailed knowledge about this glycosylation is therefore crucial. We have developed a reversed-phase liquid chromatographic–mass spectrometric method,...

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Detalles Bibliográficos
Autores principales: Higel, Fabian, Demelbauer, Uwe, Seidl, Andreas, Friess, Wolfgang, Sörgel, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2013
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581771/
https://www.ncbi.nlm.nih.gov/pubmed/23371526
http://dx.doi.org/10.1007/s00216-012-6690-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581771/
https://www.ncbi.nlm.nih.gov/pubmed/23371526
http://dx.doi.org/10.1007/s00216-012-6690-3

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