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Reversed-phase liquid-chromatographic mass spectrometric N-glycan analysis of biopharmaceuticals
N-Glycosylation is a common post-translational modification of monoclonal antibodies with a potential effect on the efficacy and safety of the drugs; detailed knowledge about this glycosylation is therefore crucial. We have developed a reversed-phase liquid chromatographic–mass spectrometric method,...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581771/ https://www.ncbi.nlm.nih.gov/pubmed/23371526 http://dx.doi.org/10.1007/s00216-012-6690-3 |