EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples

AIMS: Activating mutations in the gene encoding epidermal growth factor receptor (EGFR) can confer sensitivity to EGFR tyrosine kinase inhibitors such as gefitinib in patients with advanced non-small-cell lung cancer. Testing for mutations in EGFR is therefore an important step in the treatment-deci...

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Detalles Bibliográficos
Autores principales: Ellison, Gillian, Zhu, Guanshan, Moulis, Alexandros, Dearden, Simon, Speake, Georgina, McCormack, Rose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582044/
https://www.ncbi.nlm.nih.gov/pubmed/23172555
http://dx.doi.org/10.1136/jclinpath-2012-201194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582044/
https://www.ncbi.nlm.nih.gov/pubmed/23172555
http://dx.doi.org/10.1136/jclinpath-2012-201194

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