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EGFR mutation testing in lung cancer: a review of available methods and their use for analysis of tumour tissue and cytology samples
AIMS: Activating mutations in the gene encoding epidermal growth factor receptor (EGFR) can confer sensitivity to EGFR tyrosine kinase inhibitors such as gefitinib in patients with advanced non-small-cell lung cancer. Testing for mutations in EGFR is therefore an important step in the treatment-deci...
Autores principales: | Ellison, Gillian, Zhu, Guanshan, Moulis, Alexandros, Dearden, Simon, Speake, Georgina, McCormack, Rose |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582044/ https://www.ncbi.nlm.nih.gov/pubmed/23172555 http://dx.doi.org/10.1136/jclinpath-2012-201194 |
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