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Evaluation of Allele Frequency Estimation Using Pooled Sequencing Data Simulation

Next-generation sequencing (NGS) technology has provided researchers with opportunities to study the genome in unprecedented detail. In particular, NGS is applied to disease association studies. Unlike genotyping chips, NGS is not limited to a fixed set of SNPs. Prices for NGS are now comparable to...

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Detalles Bibliográficos
Autores principales: Guo, Yan, Samuels, David C., Li, Jiang, Clark, Travis, Li, Chung-I, Shyr, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582166/
https://www.ncbi.nlm.nih.gov/pubmed/23476151
http://dx.doi.org/10.1155/2013/895496