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A highly accurate heuristic algorithm for the haplotype assembly problem

BACKGROUND: Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation in human DNA. The sequence of SNPs in each of the two copies of a given chromosome in a diploid organism is referred to as a haplotype. Haplotype information has many applications such as gene disease di...

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Detalles Bibliográficos
Autores principales: Deng, Fei, Cui, Wenjuan, Wang, Lusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582451/
https://www.ncbi.nlm.nih.gov/pubmed/23445458
http://dx.doi.org/10.1186/1471-2164-14-S2-S2