A Genetically Encoded FRET Lactate Sensor and Its Use To Detect the Warburg Effect in Single Cancer Cells

Lactate is shuttled between and inside cells, playing metabolic and signaling roles in healthy tissues. Lactate is also a harbinger of altered metabolism and participates in the pathogenesis of inflammation, hypoxia/ischemia, neurodegeneration and cancer. Many tumor cells show high rates of lactate...

Descripción completa

Detalles Bibliográficos
Autores principales: San Martín, Alejandro, Ceballo, Sebastián, Ruminot, Iván, Lerchundi, Rodrigo, Frommer, Wolf B., Barros, Luis Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582500/
https://www.ncbi.nlm.nih.gov/pubmed/23469056
http://dx.doi.org/10.1371/journal.pone.0057712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582500/
https://www.ncbi.nlm.nih.gov/pubmed/23469056
http://dx.doi.org/10.1371/journal.pone.0057712

Ejemplares similares