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Spatiotemporal Dynamics of Early DNA Damage Response Proteins on Complex DNA Lesions

The response of cells to ionizing radiation-induced DNA double-strand breaks (DSB) is determined by the activation of multiple pathways aimed at repairing the injury and maintaining genomic integrity. Densely ionizing radiation induces complex damage consisting of different types of DNA lesions in c...

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Detalles Bibliográficos
Autores principales: Tobias, Frank, Löb, Daniel, Lengert, Nicor, Durante, Marco, Drossel, Barbara, Taucher-Scholz, Gisela, Jakob, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582506/
https://www.ncbi.nlm.nih.gov/pubmed/23469115
http://dx.doi.org/10.1371/journal.pone.0057953