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Mechanistic Insights Revealed by the Crystal Structure of a Histidine Kinase with Signal Transducer and Sensor Domains

Two-component systems (TCSs) are important for the adaptation and survival of bacteria and fungi under stress conditions. A TCS is often composed of a membrane-bound sensor histidine kinase (SK) and a response regulator (RR), which are relayed through sequential phosphorylation steps. However, the m...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Sang, Jiayan, Wang, Jiawei, Su, Mingyan, Downey, Jennifer S., Wu, Qinggan, Wang, Shida, Cai, Yongfei, Xu, Xiaozheng, Wu, Jun, Senadheera, Dilani B., Cvitkovitch, Dennis G., Chen, Lin, Goodman, Steven D., Han, Aidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582566/
https://www.ncbi.nlm.nih.gov/pubmed/23468592
http://dx.doi.org/10.1371/journal.pbio.1001493