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Mechanistic Insights Revealed by the Crystal Structure of a Histidine Kinase with Signal Transducer and Sensor Domains
Two-component systems (TCSs) are important for the adaptation and survival of bacteria and fungi under stress conditions. A TCS is often composed of a membrane-bound sensor histidine kinase (SK) and a response regulator (RR), which are relayed through sequential phosphorylation steps. However, the m...
Autores principales: | Wang, Chen, Sang, Jiayan, Wang, Jiawei, Su, Mingyan, Downey, Jennifer S., Wu, Qinggan, Wang, Shida, Cai, Yongfei, Xu, Xiaozheng, Wu, Jun, Senadheera, Dilani B., Cvitkovitch, Dennis G., Chen, Lin, Goodman, Steven D., Han, Aidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582566/ https://www.ncbi.nlm.nih.gov/pubmed/23468592 http://dx.doi.org/10.1371/journal.pbio.1001493 |
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