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Blood-Brain Barrier Breakdown after Embolic Stroke in Rats Occurs without Ultrastructural Evidence for Disrupting Tight Junctions

The term blood-brain barrier (BBB) relates to the ability of cerebral vessels to hold back hydrophilic and large molecules from entering the brain, thereby crucially contributing to brain homeostasis. In fact, experimental opening of endothelial tight junctions causes a breakdown of the BBB evidence...

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Detalles Bibliográficos
Autores principales: Krueger, Martin, Härtig, Wolfgang, Reichenbach, Andreas, Bechmann, Ingo, Michalski, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582567/
https://www.ncbi.nlm.nih.gov/pubmed/23468865
http://dx.doi.org/10.1371/journal.pone.0056419