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Insights into the regulation of human CNV-miRNAs from the view of their target genes

BACKGROUND: microRNAs (miRNAs) represent a class of small (typically 22 nucleotides in length) non-coding RNAs that can degrade their target mRNAs or block their translation. Recent research showed that copy number alterations of miRNAs and their target genes are highly prevalent in cancers; however...

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Detalles Bibliográficos
Autores principales: Wu, Xudong, Zhang, Dinglin, Li, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582595/
https://www.ncbi.nlm.nih.gov/pubmed/23244579
http://dx.doi.org/10.1186/1471-2164-13-707