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Evolution of Bcl-2 homology motifs: homology versus homoplasy

Bcl-2 family proteins regulate apoptosis in animals. This protein family includes several homologous proteins and a collection of other proteins lacking sequence similarity except for a Bcl-2 homology (BH)3 motif. Thus, membership in the Bcl-2 family requires only one of the four BH motifs. On this...

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Detalles Bibliográficos
Autores principales: Aouacheria, Abdel, Rech de Laval, Valentine, Combet, Christophe, Hardwick, J. Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582728/
https://www.ncbi.nlm.nih.gov/pubmed/23199982
http://dx.doi.org/10.1016/j.tcb.2012.10.010