Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting β-catenin signaling

Transducer of ErbB-2.1 (Tob1), a tumor suppressor protein, is inactivated in a variety of cancers including stomach cancer. However, the role of Tob1 in gastric carcinogenesis remains elusive. The present study aimed to investigate whether Tob1 could inhibit gastric cancer progression in vitro, and...

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Detalles Bibliográficos
Autores principales: KUNDU, JUTHIKA, WAHAB, S.M. RIAJUL, KUNDU, JOYDEB KUMAR, CHOI, YOON-LA, ERKIN, OZGUR CEM, LEE, HUN SEOK, PARK, SANG GYU, SHIN, YOUNG KEE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582759/
https://www.ncbi.nlm.nih.gov/pubmed/22710759
http://dx.doi.org/10.3892/ijo.2012.1517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582759/
https://www.ncbi.nlm.nih.gov/pubmed/22710759
http://dx.doi.org/10.3892/ijo.2012.1517

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