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Tob1 induces apoptosis and inhibits proliferation, migration and invasion of gastric cancer cells by activating Smad4 and inhibiting β-catenin signaling
Transducer of ErbB-2.1 (Tob1), a tumor suppressor protein, is inactivated in a variety of cancers including stomach cancer. However, the role of Tob1 in gastric carcinogenesis remains elusive. The present study aimed to investigate whether Tob1 could inhibit gastric cancer progression in vitro, and...
Autores principales: | KUNDU, JUTHIKA, WAHAB, S.M. RIAJUL, KUNDU, JOYDEB KUMAR, CHOI, YOON-LA, ERKIN, OZGUR CEM, LEE, HUN SEOK, PARK, SANG GYU, SHIN, YOUNG KEE |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582759/ https://www.ncbi.nlm.nih.gov/pubmed/22710759 http://dx.doi.org/10.3892/ijo.2012.1517 |
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