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The membrane-raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila

The dopamine transporter (DAT) is the primary molecular target responsible for the rewarding properties of the psychostimulants amphetamine (AMPH) and cocaine. AMPH increases extracellular dopamine (DA) by promoting its nonexocytotic release via DAT-mediated efflux. Previous studies in heterologous...

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Detalles Bibliográficos
Autores principales: Pizzo, Andrea B., Karam, Caline S., Zhang, Yuchao, Yano, Hideaki, Freyberg, Robin J., Karam, David S., Freyberg, Zachary, Yamamoto, Ai, McCabe, Brian D., Javitch, Jonathan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582826/
https://www.ncbi.nlm.nih.gov/pubmed/22710269
http://dx.doi.org/10.1038/mp.2012.82