Cargando…
The membrane-raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila
The dopamine transporter (DAT) is the primary molecular target responsible for the rewarding properties of the psychostimulants amphetamine (AMPH) and cocaine. AMPH increases extracellular dopamine (DA) by promoting its nonexocytotic release via DAT-mediated efflux. Previous studies in heterologous...
Autores principales: | Pizzo, Andrea B., Karam, Caline S., Zhang, Yuchao, Yano, Hideaki, Freyberg, Robin J., Karam, David S., Freyberg, Zachary, Yamamoto, Ai, McCabe, Brian D., Javitch, Jonathan A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582826/ https://www.ncbi.nlm.nih.gov/pubmed/22710269 http://dx.doi.org/10.1038/mp.2012.82 |
Ejemplares similares
-
Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain
por: Freyberg, Zachary, et al.
Publicado: (2016) -
Functional Genomic Analysis of Amphetamine Sensitivity in Drosophila
por: Karam, Caline S., et al.
Publicado: (2022) -
Dopamine D(2) receptors and the circadian clock reciprocally mediate antipsychotic drug-induced metabolic disturbances
por: Freyberg, Zachary, et al.
Publicado: (2017) -
Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT
por: Cremona, M. Laura, et al.
Publicado: (2011) -
N-Terminal Phosphorylation of the Dopamine Transporter Is Required for Amphetamine-Induced Efflux
por: Khoshbouei, Habibeh, et al.
Publicado: (2004)