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RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas

The involvement of the Ras superfamily of GTPases in the pathogenesis of rhabdomysarcoma (RMS) is not well understood. While mutant H-Ras leads to embryonal RMS (ERMS) formation in experimental animals and in Costello syndrome patients, no data exists on the potential role of Ras GTPases in the path...

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Detalles Bibliográficos
Autores principales: TARNOWSKI, MACIEJ, SCHNEIDER, GABRIELA, AMANN, GABRIELE, CLARK, GEOFFREY, HOUGHTON, PETER, BARR, FREDERIC G., KENNER, LUKAS, RATAJCZAK, MARIUSZ Z., KUCIA, MAGDA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582851/
https://www.ncbi.nlm.nih.gov/pubmed/22752028
http://dx.doi.org/10.3892/ijo.2012.1536