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Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: Role for ATP-sensitive K(+) channels and endoplasmic reticulum stress

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is promising for cancer treatment owing to its selective cytotoxicity against malignant cells. However, some cancer cell types, including malignant melanoma cells, are resistant to TRAIL-induced apoptosis. Therefore, drugs that can ampl...

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Detalles Bibliográficos
Autores principales: SUZUKI, YOSHIHIRO, INOUE, TOSHIO, MURAI, MAYUMI, SUZUKI-KARASAKI, MIKI, OCHIAI, TOYOKO, RA, CHISEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582902/
https://www.ncbi.nlm.nih.gov/pubmed/22613960
http://dx.doi.org/10.3892/ijo.2012.1483