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Role of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: Potential prospects for combined targeted therapeutics

Hepatocellular carcinoma (HCC) is the third leading cause of cancer death, and its incidence is increasing worldwide in an alarming manner. The development of curative therapy for advanced and metastatic HCC is a high clinical priority. The HCC genome is complex and heterogeneous; therefore, the ide...

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Detalles Bibliográficos
Autores principales: ZIMONJIC, DRAZEN B., POPESCU, NICHOLAS C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583004/
https://www.ncbi.nlm.nih.gov/pubmed/22580498
http://dx.doi.org/10.3892/ijo.2012.1474