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The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2

Polarised tissue elongation during morphogenesis involves cells within epithelial sheets or tubes making and breaking intercellular contacts in an oriented manner. Growing evidence suggests that cell adhesion can be modulated by endocytic trafficking of E-cadherin (E-cad), but how this process can b...

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Detalles Bibliográficos
Autores principales: Warrington, Samantha J., Strutt, Helen, Strutt, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583042/
https://www.ncbi.nlm.nih.gov/pubmed/23364328
http://dx.doi.org/10.1242/dev.088724